Icyatsi gishya gitanga ubuziranenge bwa Kelp Gukuramo 20% Ifu ya Fucoxanthin

1. Ingaruka zo kurwanya ibibyimba

(1) Kanseri y'uruhu

Fucoxanthin yabujije kongera ibikorwa bya ornithine decarboxylase mu ruhu rwa epidermal y'uruhu rwatewe na tetradecanoylphorbol-13-acetate (TPA), kandi cacao yabujije gukora herpesvirus y'abantu iterwa na TPA, bityo ikabuza ibibyimba by'uruhu biterwa na TPA.

(2) Kanseri y'amara

Fucoxanthin irashobora kubuza ishingwa rya kanseri yo mu nda iterwa na n-ethyl-N '-nitro-n-nitroguanidine. Fucoxanthine yabujije cyane imikurire ya kanseri y'amara, harimo Caco-2, HT-29 na DLD-1. Irashobora gutuma ADN isenyuka kanseri ya kanseri y'amara, igatera apoptose selile, kandi ikabuza kwerekana proteine ​​Bcl-2 ifitanye isano na apoptose.

Fucoxanthin irashobora kubuza ikwirakwizwa ry'umurongo wa kanseri ya kanseri y'umuntu WiDr muburyo buterwa na dose, kandi irashobora guhagarika ingirabuzimafatizo mugice cya G0 / G1 kandi igatera apoptose.

(3) Ibibyimba bya Hematologiya

Ingaruka ya fucoxanthin kuri HL-60 umurongo wa selile ikaze ya myeloid leukemia. Fucoxanthin irashobora kubuza cyane ikwirakwizwa rya selile HL-60. Ingaruka za fucoxanthin kumuntu mukuru T lymphocytike leukemia. Fucoxanthin hamwe na metabolite fucoxanol ibuza kubaho ingirabuzimafatizo T zanduye virusi ya T-selile lymphotropic virusi yo mu bwoko bwa 1 (HTLV-1) hamwe na selile T-selile ikuze.

(4) Kanseri ya prostate

Fucoxanthin irashobora kugabanya cyane igipimo cyo kubaho kwingirangingo za kanseri ya prostate kandi igatera apoptose selile. Fucoxanthin na metabolite fucoxanol irashobora kubuza ikwirakwizwa rya selile PC-3, gukora Caspase-3 no gutera apoptose.

(5) Kanseri y'umwijima

Fucoxanthoxanthine irashobora kubuza imikurire ya selile HepG2, ikabuza selile mugice cya G0 / G1, ikanabuza Rb protein fosifora kuri site ya Ser780

Ingaruka ya antioxydeant

Fucoxanthin ifite antioxydeant nziza, ndetse iruta vitamine E na vitamine C. Fucoxanthin igira ingaruka zo gukingira imvune ya fibrocyte yatewe na UV-B. Ibikorwa bya antioxydeant ya Fucoxanthin biterwa ahanini no kugenzura ibikorwa bya Na + -K + -ATPase, ndetse no kugenzura ibikorwa bya catalase na glutathione mubice na molekile biterwa no kubura retinol. Fucoxanthin ni ingirakamaro ku buzima bw'amaso, cyane cyane ingaruka zayo zo kurinda retina, ifasha mu kwirinda indwara z'amaso nka cataracte na macula degeneration.

3.Anti-inflammatory ingaruka

Fucoxanthin yabujije gusohora abunzi ba endotoxine iterwa na mediatori mu buryo buterwa na dose, kandi ingaruka zayo zo kurwanya inflammatory zagereranijwe na prednisolone, byerekana ko fucoxanthin yagize ingaruka zimwe na zimwe zo kubuza kwanduza indwara ya endotoxine, OYA, PGE2 hamwe n’ibibyimba bya nérosose. imbeba. Ingaruka zayo zo kurwanya inflammatory ahanini binyuze mukubuza gusohora OYA mubitekerezo byatewe na LPS iterwa na macrophage. Isesengura rya RT-PCR ryerekanye ko mRNA ya NO synthetase na cyclooxygenase yabujijwe na fucoxanthin, no kwerekana ibibyimba biterwa na kanseri, leukocyte interleukin IL-1β na IL-6, na mRNA viability yabujijwe na fucoxanthin. Ibisubizo byerekana ko fucoxanthin ishobora kugira uruhare runini mubisubizo bitandukanye byo gutwika.

4.Gabanya ibiro

Fucoxanthin irashobora gukuraho kwirundanya kw'amavuta muburyo bubiri. Fucoxanthin ikora proteine ​​yitwa UCP1, itera lipolysis. Itera kandi umwijima kubyara DHA, igabanya urugero rwa cholesterol.

5. Ibindi

Inkari zo mu nyanja zirimo fucoxanthin mu ndyo yazo zo mu nyanja, zigira uruhare runini muri fagocytose ya macrophage na ovulation.