NikiGinsenoside?
Ginsenoside ningirakamaro zingirakamaro za ginseng. Biri mubice bya triterpenoid glycoside kandi birashobora kugabanywa muri saponine protopanaxadiol (saponine yo mu bwoko bwa PPD), saponine protopanaxatriol (saponine yo mu bwoko bwa PPT) nubwoko bwa oleanane. Ginsenoside zirenga 40 zashyizwe mu mizi ya ginseng.
Ginsenoside igira ingaruka nyinshi zo kuvura nka antioxydeant, anti-inflammatory, vasodilation, anti-allergique, na anti-diabete. Ginsenoside zimwe na zimwe zigaragaza imiterere yazo yo kurwanya kanseri mu kugabanya kwangirika kwa ADN, kugabanya kwandura kwa nyirarureshwa, kongera ubudahangarwa bw'umubiri hamwe na apoptose. Byongeye kandi, ginsenoside irashobora kunoza neza imikorere yimiti gakondo ya chimiotherapie kandi ikarinda kwangirika kwinyama zisanzwe.
Ibirimo bya Ginsenoside Yuzuye Mubice Bitandukanye bya Ginseng
| Igice | Ibirimo byose bya Ginsenoside |
| Imizi | 60.5% |
| Amababi | 15% |
| Ginseng | 7,6% -12,6% |
| Imizi ya Ginseng | 8.5% -11.5% |
| Uruhu rwa Ginseng | 8.0% -8.8% |
| Ginseng taproot | 2% -7% |
| Ginseng imizi | 3% |
| Imbuto | 0.7% |
Ubwoko Nibintu bya Shimi byaGinsenoside
Ginsenoside yose ifite ibyingenzi bisa, byose birimo nucleus ya sterane steroid hamwe na atome 30 ya karubone itondekanye kumpeta enye. Bagabanijwemo amatsinda abiri ukurikije imiterere ya glycoside itandukanye: ubwoko bwa dammarane n'ubwoko bwa oleanane.
Ubwoko bwa Dammarane burimo ibyiciro bibiri:
Ubwoko bwa Ginsenoside-A, aglycone ni 20 (S) -protopanaxadiol. Harimo ginsenoside nyinshi, nka ginsenoside Rg3, Rb1, Rb2, Rb3, Rc, Rd, Rh2 na glycoside PD;
Ubwoko bwa Ginsenoside-B, aglycone ni 20 (S) -protopanaxadiol. Harimo ginsenoside Re, Rg1, Rg2, Rh1 na glycoside PT.
Ubwoko bwa Oleanane: ubwoko bwa aside oleanolike-C, aglycone ni aside oleanolike.
Saponine yuzuye ntabwo ari hemolytike, ubwoko bwa A burwanya hemolitike, mugihe ubwoko B nubwoko C ari hemolitike.
| Ubwoko bwa Ginsenoside | Ingaruka |
| Rh2 | Ifite ingaruka zo guhagarika metastasis ya selile kanseri mubindi bice, kongera ubudahangarwa bw'umubiri, no kugarura vuba umubiri. Ifite ingaruka zikomeye zo kurwanya metastasis ku ngirabuzimafatizo za kanseri, kandi irashobora kujyanwa kubagwa kugira ngo ikire ibikomere no gukira ku mubiri nyuma yo kubagwa. Bioavailable yuzuye ni (16.1 ± 11.3)%. |
| Rg | Ifite ingaruka zo gukangura sisitemu yo hagati yo hagati, kurwanya umunaniro, kunoza kwibuka no kwiga, no guteza imbere synthesis ya ADN na RNA. Ifite ingaruka zo gukangura sisitemu yo hagati yo hagati, kurwanya umunaniro, kunoza kwibuka no kwiga, no guteza imbere synthesis ya ADN na RNA. |
| Rg1 | Irashobora kugabanya vuba umunaniro, kunoza imyigire no kwibuka, no gutinda gusaza. Ifite ingaruka zo gukangura sisitemu yo hagati no guhagarika platelet. |
| Rg2 | Ifite ingaruka zo kurwanya ihungabana, itera vuba ischemia myocardial na hypoxia, ikanavura kandi ikarinda indwara z'umutima. |
| Rg3 | Irashobora gukora ku cyiciro cya G2 cyimyororokere yingirabuzimafatizo, ikabuza synthesis ya proteyine na ATP mugice cyambere cya mitoto ya kanseri ya kanseri, igabanya umuvuduko ukwirakwira no gukura kwingirangingo za kanseri, kandi ikagira ingaruka zo kubuza kwinjirira kanseri ya kanseri, kurwanya selile selile metastasis, guteza imbere kanseri yibibyimba apoptose, no kubuza imikurire ya selile. |
| Rg5 | Irinde kwinjirira kanseri ya kanseri, metastasis anti-tumor selile, guteza imbere kanseri yibibyimba apoptose, kubuza imikurire yikibyimba |
| Rb1 | Ginseng y'Abanyamerika (ginseng y'Abanyamerika) ifite ibintu byinshi kandi ifite ubushobozi bwo kugira ingaruka ku ntangangabo z'inyamaswa no gukura kw'imbeba. Ifite umurimo wo kuzamura sisitemu ya choline, kongera synthesis no kurekura acetylcholine no kunoza kwibuka. |
| Rb2 | Iterambere rya ADN na RNA, kugenzura ubwonko bigira ingaruka zo guhagarika sisitemu yo hagati yo hagati, kugabanya calcium yo mu nda, anti-okiside, gusohora radicals yubusa mumubiri no kunoza imvune ya myocardial ischemia-reperfusion. |
| Rc | Ginsenoside-Rc ni molekile ya steroid muri ginseng. Ifite umurimo wo guhagarika ingirangingo za kanseri. Irashobora kongera ibikorwa byintanga. |
| Rb3 | Irashobora kongera imikorere ya myocardial no kurinda umubiri wumubiri. Irashobora gukoreshwa mukuvura myocardial contractile yatewe nimpamvu zitandukanye. |
| Rh | Ifite ingaruka zo guhagarika sisitemu yo hagati yo hagati, hypnotic, analgesic, gutuza, antipyretike, no guteza imbere sintezamubiri ya serumu. |
| Rh1 | Ifite ingaruka zo guteza imbere ikwirakwizwa ry'umwijima no guhuza ADN, kandi irashobora gukoreshwa mu kuvura no gukumira hepatite na cirrhose. |
| R0 | Ifite anti-inflammatory, disoxifying, and anti-trombotic, ibuza gukusanya aside aside, kandi ifite ingaruka zo kurwanya hepatite kandi ikora macrophage. |
| Rh3 | Ingaruka za ginsenoside Rh3 mukwirakwiza no apoptose yingirabuzimafatizo ya muntu SW480. |
Ibikoresho birwanya ibibyimba
| Ibikoresho | Ingaruka |
| Rh2 | Ginsenoside Rh2 monomer igira ingaruka mbi kumikurire ya kanseri ya kanseri, irashobora gutera kanseri yibibyimba apoptose, ihindura itandukaniro ridasanzwe ryimikorere yibibyimba, kandi ikarwanya metastasis yibibyimba. Iyo ikoreshejwe hamwe n'imiti ya chimiotherapie, irashobora kongera imbaraga no kugabanya uburozi. Usibye ingaruka zo kurwanya ibibyimba, ginsenoside igira ingaruka zo kuzamura ubudahangarwa bw'umubiri, antibacterial, kunoza amaraso adahagije yumutima nimiyoboro yubwonko ndetse nubwonko bwamaraso, kugenzura imikorere yimitsi yo hagati, kurwanya umunaniro, no gutinda gusaza. |
| Rh1 | Irashobora kubuza kwifata no kwinjira mu ngirabuzimafatizo z'ikibyimba, ikarinda ishingwa ry'amaraso mashya y'uturemangingo twa kanseri, bityo bikabuza gukura kw'ibibyimba, gukwirakwira na metastasis, kandi bifite umurimo ukomeye wo kurwanya kanseri. Irashobora kunoza cyane kugabanuka kwingirangingo zamaraso zera ziterwa na radiotherapi, chimiotherapie no kubaga, kandi bigatuma rheologiya yamaraso ikunda kuba ibisanzwe. Ibi bikoresho bifite ingaruka zikomeye zo gukumira no kurwanya kanseri, birashobora kunoza imikorere yumuntu nimikorere yumubiri, kandi bigira ingaruka zikomeye zifatanije no kubaga hamwe na radiotherapi na chimiotherapie. |
| Rg5 | Rg5 irashobora gutera apoptose ya selile zitandukanye. Rg5 yakuwe muri ginseng nziza yumukara yagenzuwe mumasemburo yabantu. Rg5 irashobora kandi gutera apoptose no kwangirika kwa ADN mu ngirabuzimafatizo zitandukanye za kanseri y'inkondo y'umura. Ubushakashatsi bwakozwe mubushakashatsi bwa vitro bwemeje ko ginsenoside Rg5 igira ingaruka mbi kuri selile kanseri ya Esophageal. |
| Rh3 | Ginsenoside Rh3 irashobora kubuza ikwirakwizwa ry'uturemangingo twa kanseri ya kanseri y'abantu SW480 kandi igatera apoptose, kandi ingaruka ziterwa na dose kandi biterwa nigihe. |
| APPD | 20. Mu myaka yashize, itsinda ry’ubushakashatsi bwa William Jia ryo muri kaminuza ya British Columbia ryakoze ubushakashatsi ku bikorwa byo kurwanya ibibyimba bya APPD muri vivo no muri vitro, basanga bifite ingaruka ebyiri za farumasi. Ku ruhande rumwe, irashobora kwica mu buryo butaziguye ingirabuzimafatizo no kubyutsa apoptose; kurundi ruhande, irashobora kurinda neuron ibintu bya cytotoxic. |
Ni izihe nyunguGinsenoside?
Ibyiza bya ginsenoside, ibice bikora biboneka muri ginseng, ni binini kandi byagiye bikorwa ubushakashatsi bwimbitse. Inyungu zimwe zishobora guterwa na ginsenoside zirimo:
1. Imikorere yo kumenya: Ginsenoside yizwe kubushobozi bwabo bwo gushyigikira imikorere yubwenge, harimo kwibuka, kwibanda, no kumvikana neza.
2. Ingufu ningirakamaro: Ginsenoside yizera ko ifite imiterere ya adaptogenic, ifasha gushyigikira urwego rwingufu, kugabanya umunaniro, no guteza imbere ubuzima muri rusange.
3.
4. Gucunga Stress: Ginsenoside ifatwa nka adaptogene, bivuze ko ifasha umubiri kumenyera imihangayiko no guteza imbere imyumvire myiza.
5.
Ni ngombwa kumenya ko inyungu zihariye za ginsenoside ziratandukanye bitewe n'ubwoko bwa ginseng hamwe nibigize ginsenoside ihari. Kimwe nibindi byongeweho cyangwa ibicuruzwa bisanzwe, nibyiza kugisha inama inzobere mubuzima kugirango agire inama yihariye yerekeye ikoreshwa rya ginsenoside kubibazo byihariye byubuzima.
Ni ubuhe buryo bukoreshwa na Ginsenoside?
Ginsenoside ifite uburyo bwinshi bushobora gukoreshwa bitewe nuburyo butandukanye bwa farumasi. Bimwe mubisabwa bya ginsenoside harimo:
1.
2.
3. Imiti ya farumasi: Ubushakashatsi ku buryo bushobora kuvura imiti ya ginsenoside yatumye bakoresha imiti y’imiti, cyane cyane mu guteza imbere imiti y’ibihe nko kugabanuka kwubwenge, umunaniro, n’indwara ziterwa no guhangayika.
4. Amavuta yo kwisiga: Ginsenoside nayo ikoreshwa mu nganda zo kwisiga kugirango ibone inyungu zuruhu, harimo kurwanya gusaza na antioxydeant.
5. Ibiribwa n'ibinyobwa bikora: Ginsenoside yinjizwa mubiribwa n'ibinyobwa bitandukanye bikora, nk'ibinyobwa bitera imbaraga hamwe na tonique yubuzima, kugirango bitange inyungu zubuzima.
Ni izihe ngaruka ZuruhandeGinsenoside?
Ubusanzwe Ginsenoside ifatwa nkumutekano iyo ikoreshejwe mukigero gikwiye, ariko nkibintu byose bivangwa na bioactive, birashobora kugira ingaruka mbi cyane cyane iyo bikoreshejwe cyane. Ingaruka zimwe zishoboka za ginsenoside zishobora kubamo:
1. Kudasinzira: Umubare munini wa ginsenoside urashobora gutera gukabya, bigatera ingorane zo gusinzira cyangwa gusinzira.
2.
3. Umuvuduko ukabije w'amaraso: Mu bihe bidasanzwe, kunywa ginsenoside birenze urugero bishobora gutuma umuvuduko w'amaraso uzamuka.
4. Imyitwarire ya allergie: Nubwo bidasanzwe, abantu bamwe bashobora kuba allergique ya ginsenoside, biganisha ku bimenyetso nko guhubuka, guhinda, cyangwa guhumeka neza.
5. Ingaruka za Hormone: Ginsenoside irashobora kugira ingaruka zoroheje za hormone, kandi rimwe na rimwe, zishobora gukorana n'imiti ijyanye na hormone cyangwa imiterere.
Ni ngombwa kumenya ko ingaruka za ginsenoside zishobora gutandukana bitewe numuntu ku giti cye, ubwoko bwihariye bwa ginseng, na dosiye. Kimwe nibindi byongeweho cyangwa ibicuruzwa bisanzwe, nibyiza kugisha inama inzobere mubuzima mbere yo gukoresha ginsenoside, cyane cyane kubafite ubuzima bubi cyangwa abafata imiti.
Ibibazo bifitanye isano Urashobora gushimishwa:
Ninde utagomba gufata ginseng?
Abantu bamwe bagomba kwitonda cyangwa kwirinda gufata ginseng, harimo:
1. Abagore batwite cyangwa bonsa: Umutekano wa ginseng mugihe cyo gutwita no konsa ntabwo wigeze wigwa cyane, kubwibyo rero birasabwa kwirinda kuyikoresha muri ibi bihe.
2. Abantu bafite ikibazo cya Autoimmune: Ginseng irashobora gukangura ubudahangarwa bw'umubiri, bushobora kongera imiterere ya autoimmune. Nibyiza ko abantu bafite ikibazo cya autoimmune babaza inzobere mubuzima mbere yo gukoresha ginseng.
3. Abantu bafite ikibazo cyo kuva amaraso: Ginseng irashobora kugira ingaruka zoroheje zo kurwanya anticagulant, bityo abantu bafite ikibazo cyo kuva amaraso cyangwa abafata imiti yangiza amaraso bagomba gukoresha ginseng bitonze kandi bayobowe n’ushinzwe ubuzima.
4.
5. Abafite ikibazo cyo kudasinzira cyangwa guhangayika: Ginseng irashobora kugira ingaruka zitera imbaraga, bityo abantu bafite ikibazo cyo kudasinzira cyangwa guhangayika bagomba kwitonda mugihe bakoresha ginseng, cyane cyane muri dosiye nyinshi.
Ginsenoside ni steroid?
Ginsenoside ntabwo ari steroid. Nitsinda ryibintu bisanzwe biboneka mubihingwa bya ginseng. Mugihe ginsenoside ishobora kugira inyungu zitandukanye mubuzima, iratandukanye kandi ikora itandukanye na steroid. Steroide ni icyiciro cya hormone na lipide bigira uruhare runini muburyo bwo guhinduranya umubiri, imikorere yumubiri, nibindi bikorwa bya physiologique. Ibinyuranye na byo, ginsenoside ni saponine, ubwoko bwa glycoside, kandi bizwiho imiterere ya adaptogenic kandi iteza imbere ubuzima
Ninde ginseng ufite hejuruginsenoside?
Ubwoko bwa ginseng bufite ginsenoside nyinshi ni Panax ginseng, izwi kandi nka ginseng yo muri Aziya cyangwa Koreya. Ubu bwoko bwa ginseng buzwiho kuba bwinshi bwa ginsenoside, aribwo buryo bwa bioactive butera inyungu nyinshi z’ubuzima. Panax ginseng ihabwa agaciro cyane mubuvuzi gakondo kandi ikoreshwa kenshi mubishobora guhinduka no guhuza imbaraga. Iyo ushakisha ibicuruzwa bya ginseng birimo ibintu byinshi bya ginsenoside, Panax ginseng ni amahitamo akunzwe.
Nibyiza gufata ginseng buri munsi?
Mubisanzwe bifatwa nkumutekano kubantu benshi gufata ginseng burimunsi mugihe gito. Nyamara, kumara igihe kirekire gukoresha ginseng bishobora gutera ingaruka mbi cyangwa imikoranire n'imiti. Niyo mpamvu, ni ngombwa gukoresha ginseng iyobowe ninzobere mu buzima, cyane cyane niba uteganya kuyifata buri munsi mugihe kinini. Kugisha inama hamwe nubuvuzi birashobora gufasha kwemeza ko ginseng ikwiranye nubuzima bwawe bwihariye kandi ko idakorana nimiti iyo ari yo yose cyangwa ibihe byahozeho.
Ginseng yongera testosterone?
Ginseng yasabwe kugira ingaruka zishobora kuba kurwego rwa testosterone, nubwo ibimenyetso bidashidikanywaho. Ubushakashatsi bumwe bwerekanye ko ginseng ishobora kugira ingaruka nke kurwego rwa testosterone, bishoboka mugushigikira uburyo bugira uruhare mukubyara testosterone. Nyamara, ubushakashatsi burakenewe cyane kugirango wumve neza urugero ginseng igira kuri testosterone.
Niki ginseng ikora imisemburo y'abagore?
Ginseng irashobora kugira ingaruka zishobora gutera imisemburo y'abagore, nubwo ubushakashatsi muri kano karere butuzuye. Ubushakashatsi bumwe bwerekanye ko ginseng ishobora kuba ifite imiterere ya adaptogenic ishobora gufasha gushyigikira imisemburo ya hormone ku bagore, cyane cyane mugihe cyimihangayiko cyangwa ihindagurika rya hormone. Byongeye kandi, ginseng yashakishijwe ku nyungu zishobora guterwa mu gukemura ibimenyetso bifitanye isano no gucura, nko gushyuha no guhinduka.
Igihe cyo kohereza: Nzeri-12-2024
