NikiGlabridin?
Glabridin ni flavonoide yakuwe mu mizi ya licorice (Glycyrrhiza glabra) kandi ifite ibikorwa bitandukanye byibinyabuzima nibyiza byubuzima. glabridin izwiho kuba yera cyane, antioxydeant na anti-inflammatory kandi ikoreshwa cyane mukuvura uruhu no kwisiga.
Glycyrrhiza glabra L. ni icyatsi kimaze imyaka gikura mu majyepfo y’Uburayi, Aziya, no mu karere ka Mediterane. Ihingwa cyane mu Burusiya, Espanye, Irani, n'Ubuhinde. Igihingwa cya G. glabra gifite uburebure bwa metero 1-1.5, gifite amababi mato yijimye yijimye, indabyo z'umuhondo, ubururu, na violet, hamwe na rhizome nziza.
Glabridin ni imwe muri flavonoide nyamukuru muri Glycyrrhiza glabra. Irerekana imbaraga zikomeye zo kurwanya okiside yubusa muri sisitemu ya okiside ya cytochrome P450 / NADPH, kandi irashobora guhagarika cyane radicals yubusa ikorwa mugihe cyimikorere ya metabolisme mumubiri kugirango ikumire okiside ya biomacromolecules (lipoprotein LDL, ADN) na inkuta za selile zangirika na okiside yubusa. Ibi birashobora gukumira no kuvura impinduka zimwe na zimwe ziterwa na okiside yubusa, nka atherosklerozose no gusaza kwa selile. Byongeye kandi, glabridin igira ingaruka runaka zo kugabanya lipide yamaraso hamwe n umuvuduko wamaraso. Ubushakashatsi bw’Ubutaliyani bwemeje kandi ko Glabridin igira ingaruka zo kugabanya ubushake bwo kurya, bushobora kugabanya ibinure bitagabanije ibiro. Nyuma yipimisha inshuro nyinshi, ingaruka zingenzi nizi zikurikira: 1. Kwera, kubuza melanin; 2. Ingaruka zo kurwanya inflammatory; 3. Ingaruka ya Antioxydeant; 4. Antibacterial.
Ibintu bifatika na shimi byaGlabridin
1. Imiterere yimiti
Izina ryimiti: Glabridin
Imiti yimiti: C20H20O4
Uburemere bwa molekuline: 324.37 g / mol
Ibiranga imiterere: Glabridin nuruvange rwa flavonoid hamwe nuburyo busanzwe bwa flavonoid. Igizwe nimpeta ebyiri zimpumuro nziza (A na B) ihujwe nikiraro cya karuboni eshatu kigize impeta ya pyran ifunze.
2. Ibintu bifatika
Kugaragara: Ubusanzwe Glabridin igaragara nkifu ya kirisiti yera cyangwa yera.
Gukemura:
Amazi: Gushonga nabi mumazi.
Umuti ukomoka ku buhinzi: Gukemuka mumashanyarazi nka Ethanol, methanol, na glycol ya propylene.
Ingingo yo gushonga: Hafi ya 156-158 ° C (313-316 ° F).
Impumuro: Glabridin muri rusange nta mpumuro itandukanye.
3. Ibiranga imiti
Igihagararo: Glabridin irahagaze neza mubihe bisanzwe ariko irashobora kwangirika iyo ihuye numucyo, ubushyuhe, cyangwa aside. Birasabwa kubibika ahantu hakonje, humye, kure yizuba ryinshi.
pH Ibyiyumvo: Glabridin yunvikana nimpinduka za pH kandi irashobora gutesha agaciro acide cyane cyangwa ibidukikije byibanze.
Reactivite: Nka flavonoide, glabridin irashobora guhura nibisanzwe byimiti ijyanye nibintu bya fenolike, nka okiside na conjugation.
Ni izihe nyunguGlabridin?
1. Kwera uruhu no kumurika
- Kubuza Tyrosinase: Glabridin izwi cyane kubera kwera uruhu. Irabuza ibikorwa bya tyrosinase, enzyme ikomeye mu musaruro wa melanin, bityo bikagabanya imiterere yibibara byijimye na hyperpigmentation.
- Ndetse uruhu rwuruhu: Mugabanye synthesis ya melanin, glabridin ifasha mukugera kurwego rwuruhu rwinshi ndetse no kugaragara neza.
2. Indwara ya Antioxydeant
- Ubusa Radical Scavenging: Glabridin ifite antioxydants ikomeye, ifasha mukutabogama radicals yubuntu. Ibi bigabanya imbaraga za okiside kandi birinda kwangirika kwa selile.
- Kurwanya gusaza: Igikorwa cya antioxydeant ya glabridin gifasha mukugabanya ibimenyetso byubusaza, nkumurongo mwiza, iminkanyari, hamwe nimyaka yimyaka, mukurinda uruhu kwangirika kwa okiside.
3. Ingaruka zo Kurwanya Indurwe
- Kugabanya umuriro: Glabridin yerekana imiti igabanya ubukana, ifasha mukugabanya uruhu, gutukura, no kubyimba.
- Ingaruka zo Guhumuriza: Irashobora gutuza uruhu rwarakaye kandi ni ingirakamaro mubihe nka acne, eczema, na rosacea
4. Igikorwa cyo kurwanya mikorobe
- Kubuza indwara ziterwa na virusi: Glabridin yerekanye imiti igabanya ubukana bwa bagiteri zitandukanye. Ibi bituma bigira akamaro mukurinda no kuvura indwara zuruhu.
- Kuvura Acne: Imiti igabanya ubukana na anti-inflammatory ituma glabridine igira akamaro mu kuvura acne igabanya imikurire ya bagiteri no gutwika.
5. Kurinda UV
- Photoprotection: Glabridin irashobora gutanga urwego runaka rwo kurinda imirasire ya UV. Ifasha mukugabanya kwangirika kwuruhu rwa UV, nko gutwika izuba no gufotora.
- Ingaruka ya Synergiste: Iyo ikoreshejwe ifatanije nibindi bikoresho bitanga izuba, glabridin irashobora kuzamura ingaruka zose zifotora.
6. Gukiza ibikomere
- Guteza imbere gukira: Glabridin irashobora guteza imbere gukira ibikomere kugabanya umuriro no guhagarika umutima, no gutera imbaraga ingirabuzimafatizo zuruhu.
- Kugabanya Inkovu: Irashobora kandi gufasha mukugabanya isura yinkovu mugutezimbere uruhu rwiza.
7. Kwita ku musatsi
- Ubuzima bwumutwe: Indwara ya Glabridin irwanya inflammatory na antibicrobial irashobora kugirira akamaro ubuzima bwumutwe, bikagabanya dandruff hamwe nuburakari bwumutwe.
- Gukura k'umusatsi: Mugutezimbere ubuzima bwumutwe, glabridin irashobora kandi guteza imbere imisatsi myiza.
Nibiki BikoreshwaGlabridin?
Amavuta yo kwisiga no kwita ku ruhu
1.Ibicuruzwa byera uruhu
- Kwera amavuta na serumu: Glabridin nikintu cyingenzi mubintu byinshi byera uruhu no kumurika ibicuruzwa bitewe nubushobozi bwayo bwo guhagarika ibikorwa bya tyrosinase no kugabanya umusaruro wa melanin.
- Kuvura ibibanza: Byakoreshejwe muburyo bugamije kugabanya ibibara byijimye, hyperpigmentation, hamwe nuruhu rutaringaniye.
2.Ibicuruzwa bishaje
- Kurwanya gusaza amavuta na lisansi: Imiterere ya antioxydeant ya glabridin ifasha mukugabanya ibimenyetso byubusaza, nkumurongo mwiza, iminkanyari, hamwe nu mwanya wimyaka.
- Amavuta yijisho: Akenshi ashyirwa mumavuta yijisho kugirango agabanye uruziga rwijimye no kwishongora.
3.Anti-Gutwika no Gutuza Ibicuruzwa
- Guhumuriza Gels na cream: Imiterere ya Glabridin irwanya inflammatory ituma ibera ibicuruzwa bigenewe koroshya uruhu rwarakaye cyangwa rwaka.
- Kuvura Acne: Gukoreshwa mubicuruzwa bivura acne kugirango ugabanye umuriro no gukura kwa bagiteri.
4.Ibicuruzwa birinda izuba
- Imirasire y'izuba: Glabridin irashobora gushirwa mumirasire yizuba kugirango irinde ubundi buryo bwo kwirinda kwangirika kwuruhu rwa UV.
- Nyuma yo Kwitaho: Gukoreshwa mubicuruzwa nyuma yizuba kugirango utuze kandi usane uruhu rwahiye.
Imiti
1. Imiti yibanze
- Anti-Inflammatory cream: Ikoreshwa mumiti yibanze kugirango ivure indwara zuruhu zanduye nka eczema, psoriasis, na dermatitis.
- Amavuta yo gukiza ibikomere: Bikubiye mubikorwa bigamije guteza imbere gukira ibikomere no kugabanya inkovu.
2. Amagambo yinyongera
- Inyongera za Antioxydants: Indwara ya antioxydeant ya Glabridin ituma iba ingirakamaro mu nyongeramusaruro zo mu kanwa zigamije kugabanya imihangayiko ya okiside no guteza imbere ubuzima muri rusange.
- Immune Boosters: Ikoreshwa mubyongeweho bigamije kongera imikorere yubudahangarwa bitewe na anti-inflammatory na anticicrobial.
Kwita ku musatsi
1.Ubuvuzi bukomeye
- Shampo zo Kurwanya Dandruff: Imiti igabanya ubukana bwa Glabridin na anti-inflammatory ituma igira akamaro mu kuvura indwara ya dandruff hamwe no kurwara umutwe.
- Serumu yo mu mutwe: Ikoreshwa muri serumu yo mu mutwe kugirango iteze imbere ubuzima bwiza bwumutwe kandi bishobora gutera umusatsi gukura.
2.Imisatsi
- Konderasi hamwe na Masike yimisatsi: Bikubiye mubicuruzwa byita kumisatsi kugirango birinde antioxydeant kandi bitezimbere ubuzima bwimisatsi.
Ibiribwa n'ibinyobwa
Ibiryo bikora
- Ibinyobwa byubuzima: Glabridin irashobora kongerwamo ibinyobwa byubuzima n’ibinyobwa bikora kugirango itange antioxydeant na anti-inflammatory.
- Utubari twimirire: Yifashishwa mu tubari twimirire hamwe nibiryo bigamije guteza imbere ubuzima rusange n'imibereho myiza.
Ubushakashatsi n'Iterambere
Ubushakashatsi bwibinyabuzima
- Ubushakashatsi bwa Kanseri: Glabridin yizwe kubera ubushobozi bwayo bwo kurwanya kanseri, harimo n'ubushobozi bwayo bwo kubuza imikurire ya kanseri no gutera apoptose.
- Ubushakashatsi bw'indwara zidakira: Hakozwe iperereza ku nyungu zishobora guterwa mu gucunga indwara zidakira nka diyabete n'indwara z'umutima n'imitsi bitewe na anti-inflammatory na antioxidant.
Ibibazo bifitanye isano Urashobora gushimishwa:
Bifata igihe kingana iki kugirango ikuremo ibinyomoroglabridinkoroshya uruhu?
Igihe bifata kumashanyarazi arimo ibinyomoro birimo glabridin kugirango yorohereze uruhu birashobora gutandukana bitewe nibintu byinshi, harimo kuba glabridine yibicuruzwa, inshuro zikoreshwa, ubwoko bwuruhu rwumuntu, hamwe nuburemere bwa hyperpigmentation. Dore amabwiriza rusange hamwe nibitekerezo:
1. Igihe gisanzwe
- Ibisubizo byambere: Bamwe mubakoresha barashobora gutangira kubona iterambere ryambere mumiterere yuruhu no kugabanuka kwa hyperpigmentation mugihe cyibyumweru 2 kugeza kuri 4 byakoreshejwe bihoraho.
- Ibisubizo by'ingenzi: Ingaruka zigaragara kandi zikomeye zo kumurika uruhu mubisanzwe bibaho nyuma yibyumweru 8 kugeza 12 byo kubisaba bisanzwe.
2. Ibintu bigira ingaruka nziza
Kwishyira hamwe kwa Glabridin
- Ihuriro Ryinshi: Ibicuruzwa bifite ubunini bwinshi bwa glabridin (urugero, 0.5% kugeza 1%) birashobora gutanga ibisubizo byihuse kandi bigaragara.
- Kwibanda Hasi: Ibicuruzwa bifite intumbero yo hasi birashobora gufata igihe kirekire kugirango bigaragaze ingaruka zigaragara.
Inshuro yo gusaba
- Gukoresha Buri munsi: Gukoresha ibicuruzwa rimwe cyangwa kabiri kumunsi, nkuko bisabwa, birashobora kongera imikorere no kwihutisha ibisubizo.
- Gukoresha bidahuye: Porogaramu idasanzwe irashobora gutinza ingaruka zigaragara no kugabanya imikorere rusange.
Ubwoko bwuruhu nuburyo bimeze
- Ubwoko bwuruhu: Abantu bafite uruhu rworoshye barashobora kubona ibisubizo byihuse ugereranije nabafite uruhu rwijimye.
- Uburemere bwa Hyperpigmentation: Hyperpigmentation yoroheje irashobora kwitabira byihuse kuvurwa, mugihe ibibazo bikomeye bishobora gufata igihe kirekire kugirango bigaragaze ko byateye imbere.
3. Gahunda yinyongera yo kuvura uruhu
- Kurinda izuba: Gukoresha izuba ryinshi buri munsi ningirakamaro mugihe ukoresheje ibicuruzwa byorohereza uruhu kugirango wirinde ko pigmentation ikomeza kandi ikarinda uruhu kwangirika kwa UV.
- Kuvomera neza: Kugumana uruhu neza-neza neza birashobora kongera kwinjiza no gukora neza mubicuruzwa birimo glabridine.
- Exfolisiyoneri: Exfolisiyasi isanzwe irashobora gufasha gukuraho ingirabuzimafatizo zuruhu zapfuye no guteza imbere kwinjiza ibintu bikora, bishobora kwihutisha ibisubizo.
4. Ubushakashatsi bwa Clinical nibimenyetso
- Ubushakashatsi bwa Clinical: Ubushakashatsi bumwe na bumwe bw’ubuvuzi bwerekanye ko glabridine ishobora kugabanya cyane hyperpigmentation no kunoza imiterere yuruhu mugihe cyibyumweru 8 kugeza 12 byakoreshejwe neza.
- Ubuhamya bwabakoresha: Abakoresha benshi bavuga ko babonye iterambere ryibonekeje ryuruhu rwabo no kugabanuka kwijimye mu byumweru bike kugeza kumezi make yo gusaba bisanzwe.
Ni izihe ngaruka zaglabridin?
Glabridin ifite ibikorwa bitandukanye byibinyabuzima nibyiza byubuzima, ariko rimwe na rimwe, gukoresha ibicuruzwa birimo glabridine bishobora gutera ingaruka zimwe. Ibikurikira ningaruka zishobora guterwa no kwirinda glabridin:
1. Kurakara uruhu hamwe na Allergic Reactions
Kurakara uruhu
- Ibimenyetso: Hashobora kuba harimo gutukura, kubyimba, guhinda, kubabara, cyangwa gutwika.
- Impamvu: Kumva uruhu kuri glabridin cyangwa ibindi bintu mubicuruzwa bishobora gutera uruhu ruto.
Allergic
- Ibimenyetso: Birashobora gushiramo guhubuka, erythma, kubyimba, cyangwa guhinda bikabije.
- Impamvu: Allergie ya glabridin cyangwa ibindi bikoresho mubicuruzwa, bishobora gutera allergie reaction.
2. Kumva amafoto
- Kongera ibyiyumvo byizuba: glabridin irashobora kongera uruhu rwumucyo wizuba, biganisha ku zuba cyangwa fermensitivite dermatitis.
- Kwirinda: Iyo ukoresheje ibicuruzwa birimo glabridin, birasabwa gukoresha izuba ryinshi ryizuba kandi ukirinda izuba igihe kirekire.
3. Ingaruka za Hormone
- Ibikorwa bya Hormone: Mugihe glabridin igenewe cyane cyane gukoreshwa muburyo bwihariye, bimwe mubice bigize ibinyomoro (nka acide glycyrrhizic) bizwi ko bifite ingaruka zisa na steroid zishobora kugira ingaruka kumisemburo ya hormone.
- Gutekereza: Mugihe ukoresheje ibicuruzwa birimo glabridine kubwinshi mugihe kirekire, ugomba kwitondera kureba niba hari ibimenyetso byerekana ubusumbane bwimisemburo.
4. Imikoranire nibindi bikoresho byo kuvura uruhu
- Ibishobora kubaho: glabridin irashobora gukorana nibindi bintu bikora (nka vitamine C, retinol, nibindi), bigira ingaruka nziza cyangwa byongera ingaruka zingaruka.
- Icyifuzo: Mugihe ukoresheje ibicuruzwa birimo glabridin, birasabwa kwirinda gukoresha icyarimwe ibindi bintu bikomeye bikora cyangwa kugisha inama umuganga wimpu mbere yo kuyikoresha.
5. Ingaruka Sisitemu
- Absorption Ntarengwa:glabridinikoreshwa cyane cyane mugukoresha hanze kandi ifite sisitemu nkeya, bityo ingaruka mbi za sisitemu ntizisanzwe.
- Icyitonderwa: Niba uhuye nikibazo cyose cyangwa reaction idasanzwe, ugomba guhagarika kuyikoresha ako kanya hanyuma ukabaza muganga wawe.
6. Gutwita no konsa
- Impungenge z'umutekano: Kuri ubu hari amakuru make ku mutekano wa glabridin ku bagore batwite n'abonsa.
- Icyifuzo: Abagore batwite n'abonsa bagomba kubaza umuganga wabo mbere yo gukoresha ibicuruzwa birimo glabridin.
Igihe cyo kohereza: Nzeri-21-2024
