NikiResveratrol?
Resveratrol nikintu gisanzwe kiboneka mubihingwa bimwe na bimwe, imbuto, na vino itukura. Ni iyitsinda ryibintu byitwa polifenol, bikora nka antioxydants kandi bizwiho inyungu zubuzima. Resveratrol ni nyinshi cyane mu ruhu rwinzabibu zitukura kandi yagiye ikorerwa ubushakashatsi bwinshi kubera ingaruka zishobora kugira ku bice bitandukanye byubuzima.
Ubushakashatsi bumwe bwerekana ko resveratrol ishobora kugira akamaro kubuzima bwumutima, kuko ishobora gufasha gutera imiyoboro myiza yamaraso no gutembera. Byongeye kandi, byakozweho ubushakashatsi kubishobora kurwanya anti-inflammatory na antioxydeant, bishobora kugira ingaruka kubuzima muri rusange no gusaza.
Resveratrol kandi yakozweho ubushakashatsi ku ruhare ishobora kugira mu gushyigikira ubuzima bw’ubwonko n’imikorere y’ubwenge, ndetse n’ingaruka zabyo kuri metabolism ndetse n’inyungu zishobora guterwa no gucunga ibiro.
Ibintu bifatika na shimi bya Resveratrol
Resveratrol (3-4'-5-trihydroxystilbene) nikintu kitari flavonoide polifenol. Izina ryimiti ni 3,4 ', 5-trihydroxy-1,2-diphenylethylene (3,4', 5-trihydroxystilbene), formula ya molekile ni C14H12O3, naho uburemere bwa molekile ni 228.25.
Resveratrol isukuye igaragara nkifu yumweru yumuhondo yoroheje, idafite impumuro nziza, idashonga mumazi, kandi irashobora gushonga byoroshye mumashanyarazi nka ether, chloroform, methanol, Ethanol, acetone, na acetate ya Ethyl. Ahantu ho gushonga ni 253-255 ° C, naho ubushyuhe bwa sublimation ni 261 ° C. Irashobora guhinduka umutuku hamwe nigisubizo cya alkaline nkamazi ya amoniya, kandi irashobora kwitwara hamwe na ferric chloride-potassium ferrocyanide. Uyu mutungo urashobora gukoreshwa kugirango umenye resveratrol.
Resveratrol isanzwe ifite ibyiciro bibiri, cis na trans. Bibaho cyane cyane muburyo bwo guhinduka muri kamere. Inzego zombi zirashobora guhuzwa na glucose kugirango ikore cis na trans resveratrol glycoside. Cis- na trans-resveratrol glycoside irashobora kurekura resveratrol ikorwa na glycosidase mu mara. Munsi yumucyo ultraviolet, trans-resveratrol irashobora guhinduka cis-isomers.
Uburyo bwo Gutegura
Uburyo bwo kuvoma ibimera bisanzwe
Umuzabibu, ipfundo n'ibishyimbo bikoreshwa nk'ibikoresho fatizo byo gukuramo no gutandukanya resveratrol ya peteroli, hanyuma ukabisukura. Tekinoroji nyamukuru yo kuvoma ibicuruzwa birimo gukuramo ibinyabuzima, gukuramo alkaline no gukuramo enzyme. Uburyo bushya nka microwave ifashwa gukuramo, gukuramo CO2 birenze urugero no gukuramo ultrasonic bifashwa. Intego yo kwezwa ni ugutandukanya ahanini cis- na trans-isomers ya resveratrol na resveratrol na resveratrol ya peteroli kugirango ibone trans-resveratrol. Uburyo busanzwe bwo kweza burimo chromatografiya, silika gel inkingi ya chromatografiya, chromatografi yoroheje, chromatografiya ikora cyane, nibindi.
Uburyo bwa Synthesis
Kuva ibikubiye muriresveratrolmu bimera ni bike cyane kandi ikiguzi cyo kuvanamo ni kinini, gukoresha imiti, ibinyabuzima, ubwubatsi bwa genetike nubundi buryo bwo kubona resveratrol byabaye uburyo bwingenzi mubikorwa byiterambere. Imyitwarire ya Perkin, Hech reaction, hamwe na Witting-Hormer ni uburyo bwa chimique ikuze muguhuza resveratrol, umusaruro wa 55.2%, 70%, na 35.7%. Tekinoroji yubuhanga ikoreshwa mugucunga cyangwa kunoza inzira ya biosynthesis ya resveratrol kugirango ibone umusaruro mwinshi mwinshi; uburyo nko gukoresha mutagenezi kugirango uhitemo umurongo utanga umusaruro mwinshi urashobora kongera umusaruro wa resveratrol inshuro 1.5 ~ 3.0.
Ni izihe nyunguResveratrol?
Resveratrol yagiye ikorerwa ubushakashatsi kubera inyungu zishobora guteza ubuzima. Zimwe mu nyungu zishobora guterwa na resveratrol zirimo:
1.Gusaza
Mu 2003, umwarimu wa kaminuza ya Harvard, David Sinclair n'itsinda rye bavumbuye ko resveratrol ishobora gukora acetylase kandi ikongerera igihe cy'umusemburo, ibyo bikaba byaratumye havuka ubushakashatsi bwakozwe mu kurwanya gusaza kuri resveratrol. Howitz n'abandi. yasanze resveratrol ishobora gukora nkibikorwa bikomeye byo gucecekesha amakuru acecetse 2 homolog1 (SIRT1), irashobora kwigana uburyo bwo kurwanya gusaza kubuza kaloriya (CR), kandi ikagira uruhare mukugena ubuzima buringaniye bwibinyabuzima. . CR ni inducer ikomeye ya SIRT1 kandi irashobora kongera imvugo ya SIRT1 mubice no mubice nk'ubwonko, umutima, amara, impyiko, imitsi n'ibinure. CR irashobora gutera impinduka zifatika zitinda gusaza no kongera igihe cyo kubaho, icyingenzi muri byo gishobora kongerwa 50%. . Ubushakashatsi bwemeje ko resveratrol ishobora kongera igihe cy'umusemburo, nematode, isazi z'imbuto n'amafi yo hasi.
2.Anti-tumor, kurwanya kanseri
Resveratrol igira ingaruka zikomeye zo guhagarika ingirabuzimafatizo zitandukanye nka kanseri y'imbeba hepatocellular carcinoma, kanseri y'ibere, kanseri y'amara, kanseri yo mu gifu, na leukemia. Bamwe mu bahanga bemeje ko resveratrol igira ingaruka zikomeye zo guhagarika ingirabuzimafatizo za melanoma binyuze mu buryo bwa MTT no gutembera cytometrie.
Hari amakuru avuga ko resveratrol ishobora kongera kanseri ivura kanseri kandi ikabuza neza ingaruka ziterwa na kanseri. Ariko kugeza ubu, kubera uburyo bukomeye bwa resveratrol yo kurwanya ibibyimba, abashakashatsi ntibaragera ku bwumvikane ku buryo bukoreshwa.
3.Kwirinda no kuvura indwara z'umutima
Ubushakashatsi bw’ibyorezo bwerekanye ko "Paradox y’Abafaransa" ari uko Abafaransa barya ibinure byinshi buri munsi, ariko indwara n’impfu z’indwara zifata umutima n’umutima biri hasi cyane ugereranije n’ibindi bihugu by’Uburayi. Iki kintu gishobora kuba gifitanye isano no kunywa buri munsi divayi nyinshi. , na resveratrol irashobora kuba ikintu nyamukuru gikingira. Ubushakashatsi bwerekana ko resveratrol ishobora kugabanya urugero rwa cholesterol mu maraso ihuza reseptor ya estrogene mu mubiri w’umuntu, ikabuza platine gukora uturemangingo tw’amaraso no kwizirika ku nkuta z’amaraso, bityo bikabuza no kugabanya ibibaho n’iterambere ry’indwara zifata umutima, kandi bikagabanya ibyago byo kwandura indwara z'umutima mu mubiri w'umuntu. Ibyago byindwara zifata imitsi.
4.Inkunga ya Antioxydeant:Resveratrolikora nka antioxydeant, ifasha kurinda selile kwangirika kwa okiside iterwa na radicals yubuntu. Ibi birashobora kugira ingaruka kubuzima muri rusange no gusaza.
6.
7.Metabolism no gucunga ibiro: Resveratrol yakozweho ubushakashatsi ku ngaruka zishobora kugira kuri metabolism n'uruhare rwayo mu gushyigikira gucunga neza ubuzima.
Nibiki BikoreshwaResveratrol?
Resveratrol ifite porogaramu zitandukanye kandi ikoreshwa mubice bitandukanye kubera inyungu zubuzima. Bimwe mubisabwa muri resveratrol harimo:
1.
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3. Ibiribwa n'ibinyobwa bikora: Resveratrol rimwe na rimwe yongerwa mubiribwa n'ibinyobwa bikora, nk'ibinyobwa bitera imbaraga n'ibiribwa byibanda ku buzima, kugirango bitange inyungu ku buzima.
4.
Ni izihe ngaruka za Resveratrol?
Mugihe resveratrol yizwe kubwinyungu zayo zubuzima, ni ngombwa gusuzuma ingaruka zishobora kugabanuka cyangwa imbogamizi zijyanye no kuyikoresha. Bimwe mubitekerezo byerekeranye nibibi bya resveratrol harimo:
1. Bioavailable igarukira: Resveratrol ifite bioavailable nkeya ugereranije, bivuze ko umubiri udashobora kubyakira no kubikoresha neza mugihe byafashwe mukanwa. Ibi birashobora guhindura imikorere yabyo mugutanga ingaruka zubuzima.
2. Kubura ubuziranenge: Ubwiza hamwe nubunini bwinyongera za resveratrol zirashobora gutandukana, kandi harabura kubura ubuziranenge mubikorwa byinyongera. Ibi birashobora kugora abakiriya kumenya igipimo gikwiye nubwiza bwibicuruzwa.
3.Imikoranire ishobora kubaho: Resveratrol irashobora gukorana n'imiti imwe n'imwe cyangwa ubuzima bwiza. Ni ngombwa kugisha inama inzobere mu buvuzi mbere yo gukoresha resveratrol, cyane cyane niba ufata indi miti cyangwa ufite ibibazo byubuzima.
4.
Kimwe ninyongera iyariyo yose, nibyiza ko wakoresha resveratrol witonze kandi uyobowe ninzobere mubuzima, cyane cyane niba ufite ibibazo byubuzima cyangwa ukaba ufata indi miti.
Ibibazo bifitanye isano Urashobora gushimishwa:
Ninde ugomba kwirindaresveratrol?
Abantu bamwe bagomba kwitonda cyangwa kwirinda resveratrol, cyane cyane muburyo bwuzuye. Nibyiza ko amatsinda akurikira yagisha inama inzobere mubuzima mbere yo gukoresha resveratrol:
1. Abagore batwite cyangwa bonsa: Kubera ubushakashatsi buke ku ngaruka za resveratrol mugihe cyo gutwita no konsa, birasabwa ko abagore batwite cyangwa bonsa bashakira ubuyobozi kubashinzwe ubuzima mbere yo gukoresha inyongera za resveratrol.
2.
3. Abafite imiterere ya Hormone-Sensitive: Resveratrol yakozweho ubushakashatsi ku ngaruka zishobora kugira ku mikorere ya hormone, bityo abantu bafite imiterere-karemano ya hormone cyangwa abavura imisemburo ya hormone bagomba gukoresha resveratrol bitonze kandi bakagenzurwa n’ubuvuzi.
4. Abantu bafite ikibazo cyumwijima: Ubushakashatsi bumwe bwerekanye ko urugero rwinshi rwa resveratrol rushobora kugira ingaruka ku mwijima. Abantu bafite ikibazo cyumwijima cyangwa abafata imiti ifata umwijima bagomba gukoresha resveratrol bitonze kandi bakurikiranwa nubuvuzi.
Kimwe ninyongera, nibyingenzi kugisha inama inzobere mubuzima mbere yo gukoresha resveratrol, cyane cyane niba ufite ibibazo byubuzima byihariye, ufata imiti, cyangwa ufite ubuzima bwiza.
Resveratrol ikora iki kuruhu?
Resveratrol yizera ko itanga inyungu nyinshi zishoboka kuruhu, ibyo bikaba byaratumye ishyirwa mubicuruzwa bivura uruhu. Zimwe mu ngaruka za resveratrol kuruhu zishobora kubamo:
1. Kurinda Antioxydeant: Resveratrol ikora nka antioxydeant, ifasha guhagarika radicals yubuntu no kugabanya imbaraga za okiside mu ruhu. Ibi birashobora kurinda uruhu kwangirika kw ibidukikije, nkimirasire ya UV n umwanda.
2. Kurwanya Gusaza Ibyiza: Resveratrol itekereza ko ifite ingaruka zo kurwanya gusaza, kuko ishobora gufasha kugabanya isura yimirongo myiza n’iminkanyari, kunoza uruhu rworoshye, no gushyigikira ubuzima bwuruhu muri rusange.
3.
4. Kumurika uruhu: Ubushakashatsi bumwe bwerekana ko resveratrol ishobora kugira uruhare mu kumurika uruhu nimugoroba ikagira uruhu, bishobora kugabanya isura ya hyperpigmentation.
Nibihe biribwa biri hejuru muri resveratrol?
Ibiribwa biri hejuru muri resveratrol harimo:
1. Imizabibu itukura: Resveratrol ni nyinshi cyane muruhu rwinzabibu zitukura, bigatuma divayi itukura iba resveratrol. Nyamara, ni ngombwa kunywa inzoga mu rugero, kandi andi masoko ya resveratrol arashobora guhitamo kubatayanywa.
2. Ibishyimbo: Ubwoko bumwebumwe bwibishyimbo, cyane cyane uruhu rwibishyimbo, birimo resveratrol nyinshi.
3. Blueberries: Blueberries izwiho kuba irimo antioxydeant, kandi irimo na resveratrol, nubwo ari bike ugereranije n'inzabibu zitukura n'ibishyimbo.
4. Cranberries: Cranberries nindi soko ya resveratrol, itanga urugero ruto rwuru ruganda.
5. Shokora yijimye: Ubwoko bumwebumwe bwa shokora yijimye irimo resveratrol, itanga uburyohe bwo kwinjiza iyi nteruro mumirire.
Nibyiza gufata resveratrol buri munsi?
Icyemezo cyo gufata resveratrol burimunsi kigomba gufatwa hifashishijwe inama ninzobere mu buzima, cyane cyane iyo harebwa inyongera ya resveratrol. Nubwo muri rusange resveratrol ifatwa nkumutekano iyo ikoreshejwe ku bwinshi ikunze kuboneka mu biribwa, umutekano n’inyungu zishobora kongerwa na resveratrol ya buri munsi birashobora gutandukana bitewe nubuzima bwumuntu ku giti cye, ubuvuzi buriho, nindi miti ifatwa.
Resveratrol yaba ifite ubumara bwumwijima?
Resveratrol yakozweho ubushakashatsi ku ngaruka zishobora kugira ku mwijima, kandi mu gihe isanzwe ifatwa nk'umutekano iyo ikoreshejwe ku bwinshi ikunze kuboneka mu biribwa, hari ibimenyetso bimwe byerekana ko urugero rwa resveratrol rushobora kugira ingaruka ku mwijima. Ubushakashatsi bumwe bwerekanye ko urugero rwinshi rwa resveratrol rushobora gutera uburozi bwumwijima mubihe bimwe.
Ni ngombwa kumenya ko ubushakashatsi kuri iyi ngingo bukomeje, kandi ubushobozi bw’uburozi bw’umwijima bushobora guterwa nimpamvu nka dosiye, igihe ikoreshwa, hamwe nubuzima bwa buri muntu. Kimwe ninyongera, nibyiza kugisha inama inzobere mubuzima mbere yo gukoresha resveratrol, cyane cyane niba ufite ibibazo byubuzima cyangwa ukaba ufata indi miti ishobora kugira ingaruka kumikorere yumwijima.
Resveratrol ni mbi kumpyiko?
Hariho ibimenyetso bike byerekana ko resveratrol ari mbi kumpyiko. Nyamara, kimwe nibindi byose, ni ngombwa kwegera imikoreshereze yabyo witonze, cyane cyane niba ufite impyiko zihari cyangwa urimo gufata imiti ishobora kugira ingaruka kumikorere yimpyiko. Nibyiza kugisha inama inzobere mubuzima kugirango umenye niba inyongera ya resveratrol ikwiranye nubuzima bwawe bwihariye, cyane cyane niba ufite impungenge ziterwa n'ingaruka zishobora kugira ku buzima bwimpyiko.
Ibyo kutavangaresveratrol?
Mugihe uteganya kuzuza resveratrol, ni ngombwa kumenya imikoranire ishobora kuba hamwe nibindi bintu. Bimwe mubitekerezo kubyo kutavanga na resveratrol harimo:
1.
2. Nibyiza kugisha inama inzobere mubuzima mbere yo guhuza resveratrol nibindi byongera antioxydeant.
3. Imiti imwe n'imwe: Resveratrol irashobora gukorana n'imiti yihariye, harimo n'iy'umwijima. Ni ngombwa kuganira ku mikoranire ishobora kuba ninzobere mu buzima, cyane cyane niba ufata indi miti.
Kimwe ninyongera iyo ari yo yose, ni ngombwa gushaka ubuyobozi kubashinzwe ubuzima kugirango hamenyekane imikoreshereze ikwiye ya resveratrol ishingiye kumiterere yubuzima bwa buri muntu ndetse n’imikoranire ishobora kuba hamwe nibindi bintu.
Nshobora gukoresha vitamine C hamwe na resveratrol?
Nibyo, urashobora gukoresha vitamine C hamwe na resveratrol. Mubyukuri, ubushakashatsi bumwe bwerekana ko guhuza resveratrol na vitamine C bishobora kongera ingaruka za antioxydeant yibintu byombi. Vitamine C ni antioxydants izwi cyane ishobora kuzuza inyungu zishobora guterwa na resveratrol. Ariko, kimwe nibindi byose byongeweho, birasabwa kugisha inama inzobere mu buvuzi kugira ngo umenye neza ko ibyo bihuza bikwiranye n’ubuzima bwawe bwite no kuganira ku mikoranire iyo ari yo yose cyangwa ibitekerezo.
Igihe cyo kohereza: Nzeri-09-2024
