• NikiPQQ ?
PQQ, izina ryuzuye ni pyrroloquinoline quinone. Kimwe na coenzyme Q10, PQQ nayo ni coenzyme ya reductase. Mu rwego rwinyongera yimirire, mubisanzwe bigaragara nkumuti umwe (muburyo bwumunyu wa disodium) cyangwa muburyo bwibicuruzwa byahujwe na Q10.
Umusaruro usanzwe wa PQQ ni muto cyane. Ibaho mubutaka na mikorobe, ibimera ninyama zinyamanswa, nkicyayi, natto, kiwifruit, na PQQ nabyo bibaho mubice byumuntu.
PQQifite imikorere myinshi yumubiri. Irashobora guteza imbere mitochondriya mishya mu ngirabuzimafatizo (mitochondria yitwa "inganda zitunganya ingufu za selile"), kugirango umuvuduko wa synthesis yingufu za selile ushobora kwiyongera cyane. Byongeye kandi, PQQ yemejwe mu bushakashatsi bw’inyamaswa n’abantu kugira ngo isinzire, igabanye urugero rwa cholesterol, igabanye imbaraga za okiside, yongere ubuzima, iteza imbere imikorere y’ubwonko kandi igabanya ububabare.
Muri 2017, itsinda ry’ubushakashatsi rigizwe na Porofeseri Hiroyuki Sasakura n’abandi bo muri kaminuza ya Nagoya mu Buyapani ryashyize ahagaragara ibyavuye mu bushakashatsi bwabo mu kinyamakuru "IKINYAMAKURU CYA CELL SCIENCE". Coenzyme pyrroloquinoline quinone (PQQ) irashobora kongera ubuzima bwa nematode.
• Ni izihe nyungu z'ubuzimaPQQ ?
PQQ iteza imbere Mitochondria
Mu bushakashatsi bw’inyamaswa, abashakashatsi bo muri kaminuza ya Californiya basanze PQQ ishobora guteza imbere umusaruro wa mitochondriya nzima. Muri ubu bushakashatsi, nyuma yo gufata PQQ ibyumweru 8, umubare wa mitochondriya mu mubiri wikubye kabiri. Mu bundi bushakashatsi bw’inyamaswa, ibisubizo byagaragaje ko ubudahangarwa bwagabanutse ku buryo bugaragara kandi umubare wa mitochondriya wagabanutse utiriwe ufata PQQ. Iyo PQQ yongeye kongerwaho, ibi bimenyetso byagarutsweho vuba.
Kuraho uburibwe no kwirinda arthritisAntioxidant & kurinda imitsi
Abageze mu zabukuru bakunze guhangayikishwa na rubagimpande, nacyo kikaba ari ikintu cyingenzi kiganisha ku bumuga. Ubushakashatsi bwerekanye ko impfu rusange z’abarwayi barwaye rubagimpande ya rubagimpande ziri hejuru ya 40% ugereranije n’abaturage muri rusange. Kubwibyo, abahanga mu bya siyansi bashakishaga uburyo bwo kwirinda no kugabanya indwara ya rubagimpande. Ubushakashatsi buherutse gusohoka mu kinyamakuru Inflammation bwerekana koPQQirashobora kuba umukiza wa rubagimpande abashakashatsi bagiye bashaka.
Mu igeragezwa ry’amavuriro y’abantu, abahanga biganye umuriro wa chondrocyte mu muyoboro wapimwe, batera PQQ mu itsinda rimwe ry’utugingo ngengabuzima, kandi ntibatera irindi tsinda. Ibisubizo byerekanye ko urwego rwa kolagen yangiza imisemburo (matrix metalloproteinase) mu itsinda rya chondrocytes itatewe na PQQ yiyongereye ku buryo bugaragara.
Binyuze muri vitro no mu bushakashatsi bwa vivo, abahanga mu bya siyansi basanze PQQ ishobora kubuza irekurwa ry’ingirabuzimafatizo ziterwa na fibrotic synovial selile mu ngingo, mu gihe ibuza gukora ibintu byandikirwa mu kirere bitera umuriro. Muri icyo gihe, abahanga basanze kandi PQQ ishobora kugabanya ibikorwa byimisemburo yihariye (nka matrix metalloproteinase), isenya ubwoko bwa 2 kolagen mu ngingo kandi ikangiza ingingo.
Antioxidant & kurinda imitsi
Ubushakashatsi bwabonye koPQQigira ingaruka za neuroprotective on imbeba yo hagati yubwonko bwangirika nindwara ya Parkinson iterwa na rotenone.
Imikorere mibi ya Mitochondrial hamwe na stress ya okiside byagaragaye ko ari yo nyirabayazana w'indwara ya Parkinson (PD). Ubushakashatsi bwerekanye ko PQQ igira ingaruka zikomeye za antioxydeant kandi irashobora kurinda ischemie yubwonko mu kurwanya imihangayiko ya okiside. Igisubizo cya oxydeide gifatwa nkimwe munzira zingenzi ziganisha kuri selile apoptose. PQQ irashobora kurinda selile SH-SY5Y kwirinda rotenone (agent ya neurotoxic) -yatewe na cytotoxicity. Abahanga mu bya siyansi bakoresheje uburyo bwa PQQ kugira ngo birinde apoptose iterwa na rotenone, bagarura ubushobozi bwa mitochondrial membrane, kandi babuza umusaruro w’ubwoko bwa ogisijeni (ROS).
Muri rusange, ubushakashatsi bwimbitse ku ruhare rwaPQQmubuzima bwumubiri birashobora gufasha abantu kwirinda neza gusaza.
Isoko RishyaPQQIfu / Capsules / Ibinini / Gummies
Igihe cyo kohereza: Ukwakira-26-2024
