Bacopa monnieri, bizwi kandi nka brahmi muri Sanskrit na tonic ubwonko mucyongereza, ni icyatsi gikunze gukoreshwa na Ayurvedic. Ubushakashatsi bushya bwa siyansi buvuga ko ibyatsi byo mu Buhinde Ayurvedic Bacopa monnieri byagaragaye ko bifasha mu kwirinda indwara ya Alzheimer (AD). Iri suzuma ryasohotse mu kinyamakuru Science Drug Target Insights, ryakozwe n'itsinda ry'abashakashatsi bo muri Maleziya bo muri kaminuza ya Taylor yo muri Amerika maze risuzuma ingaruka z'ubuzima bwa bacoside, ibinyabuzima bigize uruganda.
Abashakashatsi bagaragaje ubushakashatsi bubiri bwakozwe mu mwaka wa 2011, abashakashatsi bavuze ko bacoside ishobora kurinda ubwonko kwangirika kwa okiside ndetse no kugabanuka kw’ubwenge bitewe n'imyaka myinshi. Nka glycoside idafite polar, bacoside irashobora kurenga inzitizi yubwonko bwamaraso binyuze mumyanya yoroheje ya lipide-yunganirwa. Hashingiwe ku bushakashatsi bwabanje, abashakashatsi bavuze ko bacoside ishobora kandi kunoza imikorere y’ubwenge bitewe n’imiterere y’ubusa.
Izindi nyungu zubuzima bwabacosideharimo kurinda neuron uburozi bwa Aβ buterwa n'uburozi, peptide igira uruhare runini mu gutera indwara ya AD kuko ishobora guteranira muri fibrile ya amyloide idashonga. Iri suzuma ryerekana uburyo bukoreshwa bwa Bacopa monnieri mubikorwa byubwenge na neuroprotective, kandi phytoconstituents yayo irashobora gukoreshwa mugutezimbere imiti mishya.Ibimera byinshi gakondo birimo imvange zingirakamaro zivanze nibikorwa bitandukanye bya farumasi nibinyabuzima, cyane cyane Bacopa monnieri, ikoreshwa nk'imiti gakondo no mugutezimbere ibicuruzwa birwanya gusaza.
Inyungu esheshatu zaBacopa Monnieri
1.Gutezimbere Kwibuka no Kumenya
Bacopa ifite inyungu nyinshi zikurura, ariko birashoboka ko izwi cyane kubushobozi bwayo bwo kunoza kwibuka no kumenya. Uburyo bwibanze bukoreshwaBakopabyongera kwibuka no kumenya ni muburyo bwiza bwo gutumanaho. By'umwihariko, ibyatsi biteza imbere no gukwirakwira kwa dendrite, byongera ibimenyetso byerekana imitsi.
Icyitonderwa: Dendrite ni ishami ryagutse ryimyanya myakura yakira ibimenyetso byinjira, bityo rero gushimangira izo "nsinga" zo gutumanaho kwa nervice amaherezo byongera imikorere yubwenge.
Ubushakashatsi bwerekanye ko Bacoside-A itera ingirabuzimafatizo, bigatuma synaps yakira neza imitsi yinjira. Bacopa yerekanwe kandi kongera ubushobozi bwo kwibuka no kumenya mugukangura ibikorwa bya hippocampal mukongera ibikorwa bya protein kinase mumubiri, bihindura inzira zitandukanye.
Kubera ko imvubu ari ingenzi mu bikorwa hafi ya byose byo kumenya, abashakashatsi bemeza ko ubu ari bumwe mu buryo bw'ibanze Bacopa yongerera imbaraga ubwonko.
Ubundi bushakashatsi bwerekanye ko kuzuza buri munsi hamweBacopa monnieri(kuri dosiye ya 300-640 mg kumunsi) irashobora gutera imbere:
Kwibuka gukora
Kwibuka ahantu
Kwibuka ubwenge
Icyitonderwa
Igipimo cyo kwiga
Guhuriza hamwe kwibuka
Igikorwa cyo kwibuka cyatinze
Kwibuka ijambo
Kwibuka
2.Gabanya Guhangayika no Guhangayika
Yaba imari, imibereho, umubiri, ubwenge, cyangwa amarangamutima, guhangayika nikibazo cyambere mubuzima bwabantu benshi. Ubu kuruta ikindi gihe cyose, abantu barashaka guhunga muburyo bwose bukenewe, harimo ibiyobyabwenge n'inzoga. Nyamara, ibintu nkibiyobyabwenge n'inzoga birashobora kugira ingaruka mbi kubuzima bwo mumutwe no mumubiri.
Urashobora gushimishwa no kubimenyaBakopaifite amateka maremare yo gukoresha nka sisitemu ya nervice tonic kugirango igabanye ibyiyumvo byo guhangayika, guhangayika, no guhangayika.Ibyo biterwa na Bacopa imitekerereze ya adaptogenique, ituma umubiri wacu ufite ubushobozi bwo guhangana, gukorana, no gukira imihangayiko (mumutwe, kumubiri , n'amarangamutima). Bacopa ikoresha ibyo biranga imiterere yo guhuza n'imihindagurikire y'ikirere bitewe no kugenzura imiyoboro ya neurotransmitter, ariko iki cyatsi cya kera nacyo kigira ingaruka kuri cortisol.
Nkuko ushobora kuba ubizi, cortisol niyo misemburo yibanze yumubiri. Guhangayikishwa cyane no kuzamuka kwa cortisol birashobora kwangiza ubwonko bwawe.Mu byukuri, abahanga mu bumenyi bw'imyororokere basanze imihangayiko idakira ishobora gutera impinduka ndende mu miterere y'ubwonko n'imikorere, bigatuma habaho gukabya gukabije kwa poroteyine zimwe na zimwe zangiza neurone.
Guhangayika karande kandi biganisha ku kwangiza okiside kuri neuron, bishobora kugira ingaruka mbi zitandukanye, harimo:
Gutakaza kwibuka
Urupfu rwa selile
Kubangamira gufata ibyemezo
Atrophy yubwonko bwubwonko.
Bacopa monnieri ifite imbaraga zikomeye zo kugabanya ibibazo, neuroprotective. Ubushakashatsi bwabantu bwerekanye ingaruka zijyanye na adaptogenic ya Bacopa monnieri, harimo no kugabanya cortisol. Cortisol yo hepfo itera kugabanya ibyiyumvo byo guhangayika, bidashobora kunoza umwuka gusa, ahubwo binongera kwibanda no gutanga umusaruro. Byongeye kandi, kubera ko Bacopa monnieri igenga dopamine na serotonine, irashobora guhindura impinduka ziterwa no guhangayika muri dopamine na serotonine muri hippocampus na cortex ibanziriza iyindi, bikomeza gushimangira imiterere ya adaptogenic yiki cyatsi.
Bacopa monnieribyongera kandi umusaruro wa hydroxylase ya tryptophan (TPH2), enzyme ningirakamaro mubikorwa bitandukanye bya sisitemu yo hagati yibikorwa bya nervice, harimo na synthesis ya serotonine. Icy'ingenzi cyane, bacoside-A, kimwe mu bintu byingenzi bikora muri Bacopa monnieri, byagaragaye ko bizamura ibikorwa bya GABA. GABA ni neurotransmitter ituje, ibuza. Bacopa monnieri irashobora kugenzura ibikorwa bya GABA no kugabanya ibikorwa bya glutamate, bishobora gufasha kugabanya ibyiyumvo byo guhangayika mugabanya imikorere ya neuron ishobora gukabya. Igisubizo cyanyuma kigabanya ibyiyumvo byo guhangayika no guhangayika, kunoza imikorere yubwenge, nibindi byinshi by '"kumva -ibyiza ”vibe.
Igihe cyo kohereza: Ukwakira-08-2024
