TanshinoneⅡA 99% Mukora Nshya Icyatsi TanshinoneⅡA 99% Yinyongera
Ibisobanuro ku bicuruzwa
Tanshinone, bizwi kandi nka tanshinone yuzuye, ni ibinure bikungahaye kuri fenanthrenequinone hamwe ningaruka ya antibacterial yakuwe mubuvuzi gakondo bwabashinwa Salvia miltiorrhiza (igihingwa cya Lamiaceae Salvia miltiorrhiza umuzi), aho tanshinone I, tanshinone IIA, tanshinone IIB, cryptotanshinone, na isocryptozolin. Hariho monomers zirenga 10 zirimo tanshinone, muri zo harimo 5 monomers: cryptotanshinone, dihydrotanshinone II, hydroxytanshinone, methyl tanshinone, na tanshinone IIB, bigira ingaruka za antibacterial, ndetse no kurwanya inflammatory no gukonjesha. Tanshinone IIA sodium sulfonate, ibicuruzwa bya sulfonone ya tanshinone IIA, bishonga mumazi. Igeragezwa rya Clinical ryerekanye ko rifite ingaruka zikomeye mu kuvura angina pectoris hamwe ningaruka nke. Numuti mushya wo kuvura indwara zifata umutima. Tanshinone ifite imirimo myinshi nka antibacterial, anti-inflammatory, itera umuvuduko w'amaraso no guteza imbere gukira ibikomere. Nta ngaruka zigaragara nyuma yo gukoresha igihe kirekire.
Tanshinone IIAni orange-umutuku urushinge rumeze nka kirisiti (EtOAc), mp 209～210 ℃. Byoroshye gushonga muri Ethanol, acetone, ether, benzene nindi miti ikungahaye, gushonga gato mumazi.
COA
| Ibintu | Ibisobanuro | Ibisubizo | |
| Kugaragara | Ifu yumukara | Ifu yumukara | |
| Suzuma |
| Pass | |
| Impumuro | Nta na kimwe | Nta na kimwe | |
| Ubucucike Buke (g / ml) | ≥0.2 | 0.26 | |
| Gutakaza Kuma | ≤8.0% | 4.51% | |
| Ibisigisigi kuri Ignition | ≤2.0% | 0.32% | |
| PH | 5.0-7.5 | 6.3 | |
| Ugereranije uburemere bwa molekile | <1000 | 890 | |
| Ibyuma biremereye (Pb) | ≤1PPM | Pass | |
| As | ≤0.5PPM | Pass | |
| Hg | ≤1PPM | Pass | |
| Kubara Bagiteri | 0001000cfu / g | Pass | |
| Colon Bakillus | ≤30MPN / 100g | Pass | |
| Umusemburo & Mold | ≤50cfu / g | Pass | |
| Indwara ya bagiteri | Ibibi | Ibibi | |
| Umwanzuro | Ihuze n'ibisobanuro | ||
| Ubuzima bwa Shelf | Imyaka 2 iyo ibitswe neza | ||
Imikorere
1. Kunoza indwara z'umutima: Saliviya miltiorrhiza ivamo igira ingaruka zimwe na zimwe zo kurinda umutima nimiyoboro yamaraso, irashobora kurwanya arththmia, kurwanya arteriosclerose, kunoza microcirculation, kandi ifasha kuvura indwara zifasha umutima;
2. Kubuza guteranya platine: Igicuruzwa cya Saliviya miltiorrhiza gishobora guhagarika ibikorwa byamaraso yimitsi, hanyuma bikabuza ibikorwa byo gukusanya platine;
3. Kugabanya hyperlipidemiya: Igicuruzwa cya Saliviya miltiorrhiza gishobora guhagarika ibikorwa bya sisitemu ya fibrinolytike ku rugero runaka, kandi ikagira uruhare mu kugabanya hyperlipidemiya no guhagarika aterosklerose.
Gusaba
1. Ingaruka ya Antibacterial Mubushakashatsi bwa vitro bwerekana ko tanshinone igira ingaruka zikomeye za antibacterial kuri Staphylococcus aureus kuruta berberine. Ifite kandi ingaruka mbi kuri Mycobacterium igituntu H37RV (intumbero yo hasi cyane irashobora kugera munsi ya mg / mL 1.5) nubwoko bubiri bwa trichophyton.
2. Ingaruka zo kurwanya inflammatory: Tanshinone itangwa na gavage kumbeba bifite ingaruka zigaragara zo kurwanya inflammatory. Mu cyiciro cya mbere cyerekana uburyo bwo gutwika, bigira ingaruka zikomeye zo kubuza kwiyongera kwa capillary permeability iterwa na histamine; ifite ingaruka zo kubuza kubyimba bikabije biterwa no kwera amagi, karrageenan na dextran; ifite ingaruka zo kubuza exudative formaldehyde peritonitis. Ingaruka.
3.Ingaruka za anticoagulant Tanshinone igira ingaruka zo kurwanya anticoagulant. Ingaruka irakomeye kuruta iyo protoethyl aldehyde.
Gupakira & Gutanga
